Transferrin Receptor (p90, CD71) (TFRC) (N-Term) Peptide
TFRC
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all Transferrin Receptor (TFRC) products
- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
- 蛋白结构域
- N-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- PVREEPGEDF PAARRLYWDD LKRKLSEKLD STDFTGTIKL LNENSYVPRE
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-TFRC Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
- 别名
- Trfr Peptide, LOC100219280 Peptide, tfr Peptide, cd71 Peptide, tfr1 Peptide, trfr Peptide, CD71 Peptide, T9 Peptide, TFR Peptide, TFR1 Peptide, TR Peptide, TRFR Peptide, p90 Peptide, 2610028K12Rik Peptide, AI195355 Peptide, AI426448 Peptide, AU015758 Peptide, E430033M20Rik Peptide, Mtvr-1 Peptide, Mtvr1 Peptide, transferrin receptor Peptide, TFRC Peptide, Tfrc Peptide, tfrc Peptide
- 背景
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TFRC is a cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system By similarity. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.
Alias Symbols: CD71, TFR, TFR1, TRFR, T9, TR, p90
Protein Interaction Partner: ACAP1,TF,ACAP1,CD247,CD4,GABARAP,HFE,RAB5B,RANBP9,TF,TFRC,AI837181,AT5G46630,BST2,GABARAP,HDAC5,HFE,PXK,RYK,SVIP,TF,TFRC,nef
Protein Size: 760 - 分子量
- 84 kDa
- 基因ID
- 7037
- NCBI登录号
- NM_003234, NP_003225
- UniProt
- P02786
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