Src Homology 2 Domain Containing Adaptor Protein B (SHB) (N-Term) Peptide
SHB
适用: 人
宿主: 合成
BP, WB
Quick Overview for Src Homology 2 Domain Containing Adaptor Protein B (SHB) (N-Term) Peptide (ABIN983704)
抗原
SHB
(Src Homology 2 Domain Containing Adaptor Protein B (SHB))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- N-Term
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产品特性
- This is a synthetic peptide designed for use in combination with anti-SHB antibody (Catalog #: ARP58763_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SHB (Src Homology 2 Domain Containing Adaptor Protein B (SHB))
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背景
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SHB is the adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. SHB may play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. SHB may also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. SHB may also regulate IRS1 and IRS2 signaling in insulin-producing cells.
Alias Symbols: RP11-3J10.8, bA3J10.2
Protein Interaction Partner: EPS8,FGFR1,PDGFRB,PIK3R1,SRC,src,CRK,EPS8,GRAP2,GRB2,IL2RB,IL2RG,JAK1,JAK3,KDR,LAT,LCP2,PDGFRA,PIK3R1,PLCG1,SLC39A1,SRC,VAV1,ZAP70,CRK,EPS8,FGFR1,GRB2,IL2RB,IL2RG,JAK1,JAK3,KDR,LAT,LCP2,PIK3R1,PLCG1,SRC,VAV1,ZAP70
Protein Size: 509 -
分子量
- 55 kDa
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基因ID
- 6461
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NCBI登录号
- NM_003028, NP_003019
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UniProt
- Q15464
抗原
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