A synthetic peptide for use as a blocking control in assays to test for specificity of SHB antibody, Alternative Names: SHB control peptide, SHB antibody Blocking Peptide, Anti-SHB Blocking Peptide, Src Homology 2 Domain Containing Adaptor Protein B Blocking Peptide, RP11-3J10.8 Blocking Peptide, bA3J10.2 Blocking Peptide
Optimal conditions should be determined by the investigator
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
缓冲液
PBS
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Store at -20 °C long term.
抗原
SHB
(Src Homology 2 Domain Containing Adaptor Protein B (SHB))
别名
SHB Peptide, RP11-3J10.8 Peptide, bA3J10.2 Peptide, RGD1565350 Peptide, BC028832 Peptide, SH2 domain containing adaptor protein B Peptide, src homology 2 domain-containing transforming protein B Peptide, SHB Peptide, Shb Peptide
背景
SHB is the adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. SHB may play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. SHB may also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. SHB may also regulate IRS1 and IRS2 signaling in insulin-producing cells.