Regulator of Calcineurin 1 (RCAN1) (N-Term) Peptide
RCAN1
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN982786
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Quick Overview for Regulator of Calcineurin 1 (RCAN1) (N-Term) Peptide (ABIN982786)
抗原
RCAN1
(Regulator of Calcineurin 1 (RCAN1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- N-Term
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序列
- MEDGVAGPQL GAAAEAAEAA EARARPGVTL RPFAPLSGAA EADEGGGDWS
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产品特性
- This is a synthetic peptide designed for use in combination with anti-RCAN1 Antibody(ARP57857_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RCAN1 (Regulator of Calcineurin 1 (RCAN1))
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背景
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RCAN1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease.
Alias Symbols: ADAPT78, CSP1, DSC1, DSCR1, MCIP1, RCN1
Protein Interaction Partner: GSK3B,MAP3K3,MAPK3,PPP3CA,UXT,PPP3CA,UBC
Protein Size: 252 -
分子量
- 28 kDa
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基因ID
- 1827
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NCBI登录号
- NM_004414, NP_004405
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UniProt
- P53805
抗原
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