Regulator of Calcineurin 1 (RCAN1) (C-Term) Peptide
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Quick Overview for Regulator of Calcineurin 1 (RCAN1) (C-Term) Peptide (ABIN5511914)
抗原
宿主
资源
应用范围
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蛋白结构域
- C-Term
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序列
- LHKTEFLGKE MKLYFAQTLH IGSSHLAPPN PDKQFLISPP ASPPVGWKQV
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产品特性
- This is a synthetic peptide designed for use in combination with anti-RCAN1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RCAN1 (Regulator of Calcineurin 1 (RCAN1))
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背景
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The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants.
Alias Symbols: RCAN1, ADAPT78, CSP1, DSC1, DSCR1,
Protein Size: 252 -
基因ID
- 1827
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UniProt
- P53805
抗原
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