RNA Binding Motif Protein 5 (RBM5) (N-Term) Peptide
RBM5
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN982753
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Beijing Economic Technological Development Area
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Quick Overview for RNA Binding Motif Protein 5 (RBM5) (N-Term) Peptide (ABIN982753)
抗原
RBM5
(RNA Binding Motif Protein 5 (RBM5))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- N-Term
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产品特性
- This is a synthetic peptide designed for use in combination with anti-RBM5 antibody (Catalog #: ARP38684_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RBM5 (RNA Binding Motif Protein 5 (RBM5))
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背景
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RBM5 is a component of the spliceosome A complex.It regulates alternative splicing of a number of mRNAs. RBM5 may modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. RBM5 may both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, RBM5 promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis.
Alias Symbols: FLJ39876, G15, H37, LUCA15, RMB5
Protein Interaction Partner: C1orf103,C1orf103
Protein Size: 815 -
分子量
- 92 kDa
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基因ID
- 10181
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NCBI登录号
- NM_005778, NP_005769
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UniProt
- P52756
抗原
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