RNA Binding Motif Protein 5 (RBM5) Peptide
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北京 101111
Quick Overview for RNA Binding Motif Protein 5 (RBM5) Peptide (ABIN938939)
抗原
宿主
资源
应用范围
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蛋白类型
- Synthetic
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序列
- GSDKRVSRTE RSGRYGSIID RDDRDERESR SRRRDSDYKR SSDDRRGDRY
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of RBM5 antibody,
Alternative Names: RBM5 control peptide, RBM5 antibody Blocking Peptide, Anti-RBM5 Blocking Peptide, RNA binding motif protein 5 Blocking Peptide, FLJ39876 Blocking Peptide, G15 Blocking Peptide, H37 Blocking Peptide, LUCA15 Blocking Peptide, RMB5 Blocking Peptide, RBM5, RBM-5, RBM 5, RBM-5 Blocking Peptide, RBM 5 Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- RBM5 (RNA Binding Motif Protein 5 (RBM5))
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背景
- RBM5 is a component of the spliceosome A complex.It regulates alternative splicing of a number of mRNAs. RBM5 may modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. RBM5 may both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, RBM5 promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis.
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分子量
- 92 kDa
抗原
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