8-Oxoguanine DNA Glycosylase (OGG1) (C-Term) Peptide
OGG1
适用: 人
宿主: 合成
BP, WB
-
- 抗原 See all OGG1 products
- OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))
- 蛋白结构域
- C-Term
- 宿主
- 人
-
资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- AVPVDVHMWH IAQRDYSWHP TTSQAKGPSP QTNKELGNFF RSLWGPYAGW
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-OGG1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
-
-
- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- 抗原
- OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))
- 背景
-
This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization.
Alias Symbols: HMMH, HOGG1, MUTM, OGH1
Protein Interaction Partner: CHGB,OGG1,PRKCA,XRCC1,CHGB,PRKCA,SNRPF,XRCC1
Protein Size: 322 - 分子量
- 35 kDa
- 基因ID
- 4968
- NCBI登录号
- NM_016829, NP_058438
- UniProt
- O15527
-
You are here:
