Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
产品特性
This is a synthetic peptide designed for use in combination with anti-MUC1 antibody (Catalog #: ARP41446_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
浓度
1 mg/mL
缓冲液
Final peptide concentration is 1 mg/mL in PBS.
注意事项
Avoid repeated freeze-thaw cycles.
储存条件
-20 °C
储存方法
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
抗原
MUC1
(Mucin 1 (MUC1))
背景
MUC1 is a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas.
Alias Symbols: CD227, EMA, PEM, PUM, mucin, KL-6, MAM6, PEMT, H23AG, MUC-1, MUC-1/X, MUC1/ZD, MUC-1/SEC
Protein Interaction Partner: BAX,CDKN1A,TP53,CTNNB1,EGFR,SRC,ABL1,APC,CTNNB1,CTNNB1,CTNND1,CTNND1,EGFR,EGFR,ERBB2,ERBB2,ERBB3,ERBB3,ERBB4,ERBB4,GALNT1,GALNT1,GALNT10,GALNT10,GALNT12,GALNT2,GALNT2,GALNTL2,GALNTL2,GRB2,GRB2,GSK3B,GSK3B,JUP,JUP,LCK,LYN,OSGEP,OSGEP,PRKCD,PRKCD,SIGLEC1,SOS1,SOS1,SRC,SRC,ZAP70,APC,CTNNB1,CTNND1,Ctnnb1,EGFR,ERBB2,ERBB3,ERBB4,GALNT12,GALNT4,GRB2,GSK3B,JUP,LYN,PRKCD,SOS1,SRC