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Mucin 1 (MUC1) (C-Term) Peptide

MUC1 适用: 人 宿主: 合成 BP, IHC
产品编号 ABIN1540997
发货至: 中国
  • 抗原 See all MUC1 products
    MUC1 (Mucin 1 (MUC1))
    蛋白结构域
    C-Term
    宿主
    资源
    • 18
    合成
    应用范围
    Blocking Peptide (BP), Immunohistochemistry (IHC)
    序列
    GCAGHCLSHC LGCLSVPPKE LRAAGHLSSP GYLPSYERVP HLPHPWALCA
    产品特性
    This is a synthetic peptide designed for use in combination with anti-MUC1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    MUC1 (Mucin 1 (MUC1))
    别名
    CA 15-3 Peptide, CD227 Peptide, EMA Peptide, H23AG Peptide, KL-6 Peptide, MAM6 Peptide, MCKD1 Peptide, MUC-1 Peptide, MUC-1/SEC Peptide, MUC-1/X Peptide, MUC1/ZD Peptide, PEM Peptide, PEMT Peptide, PUM Peptide, Muc-1 Peptide, mucin 1, cell surface associated Peptide, mucin 1, transmembrane Peptide, MUC1 Peptide, Muc1 Peptide
    背景
    This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.

    Alias Symbols: CD227, EMA, H23AG, KL-6, MAM6, PEM, PEMT, PUM, MUC-1, MUC-1/X, MUC1/ZD, MUC-1/SEC

    Protein Size: 158
    分子量
    14 kDa
    基因ID
    4582
    NCBI登录号
    NM_001044393, NP_001037858
    UniProt
    Q7Z538
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