Mucin 1 (MUC1) (Middle Region) Peptide
MUC1
适用: 人
宿主: 合成
BP, WB, IHC
产品编号 ABIN980372
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Mucin 1 (MUC1) (Middle Region) Peptide (ABIN980372)
抗原
MUC1
(Mucin 1 (MUC1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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蛋白结构域
- Middle Region
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产品特性
- This is a synthetic peptide designed for use in combination with anti-MUC1 antibody (Catalog #: ARP41444_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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Mucin 1 (MUC1) peptide (Ovalbumin)
MUC1 适用: 人 宿主: 合成 WB, Imm, SDS
Mucin 1 (MUC1) (AA 902-941) peptide (His tag)MUC1 适用: 人 宿主: 合成 BP, Imm
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MUC1 (Mucin 1 (MUC1))
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背景
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MUC1 is a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined.
Alias Symbols: CD227, EMA, H23AG, MAM6, PEM, PEMT, PUM, KL-6, MUC-1, MUC-1/X, MUC1/ZD, MUC-1/SEC
Protein Interaction Partner: BAX,CDKN1A,TP53,CTNNB1,EGFR,SRC,ABL1,APC,CTNNB1,CTNNB1,CTNND1,CTNND1,EGFR,EGFR,ERBB2,ERBB2,ERBB3,ERBB3,ERBB4,ERBB4,GALNT1,GALNT1,GALNT10,GALNT10,GALNT12,GALNT2,GALNT2,GALNTL2,GALNTL2,GRB2,GRB2,GSK3B,GSK3B,JUP,JUP,LCK,LYN,OSGEP,OSGEP,PRKCD,PRKCD,SIGLEC1,SOS1,SOS1,SRC,SRC,ZAP70,APC,CTNNB1,CTNND1,Ctnnb1,EGFR,ERBB2,ERBB3,ERBB4,GALNT12,GALNT4,GRB2,GSK3B,JUP,LYN,PRKCD,SOS1,SRC
Protein Size: 159 -
分子量
- 14 kDa
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基因ID
- 4582
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NCBI登录号
- NM_001044392, NP_001037857
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UniProt
- Q7Z550
抗原
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