Metastasis Associated 1 (MTA1) Peptide
MTA1
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN980315
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Beijing Economic Technological Development Area
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Quick Overview for Metastasis Associated 1 (MTA1) Peptide (ABIN980315)
抗原
MTA1
(Metastasis Associated 1 (MTA1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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产品特性
- This is a synthetic peptide designed for use in combination with anti-MTA1 antibody (Catalog #: ARP37737_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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Metastasis Associated 1 (MTA1) peptide
MTA1 适用: 人 宿主: 合成 BP, Imm
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MTA1 (Metastasis Associated 1 (MTA1))
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背景
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MTA1 encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. MTA1 was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling.
Protein Interaction Partner: BLOC1S1,ITGB3BP,MNAT1,BLOC1S1,CCNH,DDX18,DYNLL1,ESR1,GPR183,GRB2,HDAC1,HDAC2,HIF1A,ITGB3BP,MNAT1,RBBP4,SH3GLB1,TH1L,TP53,ATR,CCNH,CDK7,CHD4,ESR1,FOXP1,GPR183,HDAC1,HDAC2,HIF1A,MBD3L1,MNAT1,MTA1,MTA2,NAA10,RBBP4,RBBP7,SIN3A,TH1L,TP53
Protein Size: 430 -
分子量
- 47 kDa
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基因ID
- 9112
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NCBI登录号
- NM_001203258
抗原
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