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Metastasis Associated 1 (MTA1) (Middle Region) Peptide

MTA1 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN5511358
发货至: 中国
  • 抗原 See all MTA1 products
    MTA1 (Metastasis Associated 1 (MTA1))
    蛋白结构域
    Middle Region
    宿主
    资源
    • 5
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    QADITDLLKE GEEDGRDQSR LETQVWEAHN PLTDKQIDQF LVVARSVGTF
    产品特性
    This is a synthetic peptide designed for use in combination with anti-MTA1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    MTA1 (Metastasis Associated 1 (MTA1))
    别名
    Tex22 Peptide, metastasis associated 1 Peptide, metastasis associated 1 L homeolog Peptide, MTA1 Peptide, Mta1 Peptide, mta1.L Peptide
    背景
    This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. Two transcript variants encoding different isoforms have been found for this gene.

    Protein Size: 430
    基因ID
    9112
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