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Methionyl Aminopeptidase 2 (METAP2) Peptide

METAP2 适用: 人 宿主: 合成 BP, IHC, WB
产品编号 ABIN979997
发货至: 中国
  • 抗原 See all METAP2 products
    METAP2 (Methionyl Aminopeptidase 2 (METAP2))
    宿主
    资源
    • 1
    合成
    应用范围
    Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-METAP2 antibody (Catalog #: ARP52266_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    METAP2 (Methionyl Aminopeptidase 2 (METAP2))
    别名
    metap2 Peptide, MGC53792 Peptide, METAP2 Peptide, GB13458 Peptide, DDBDRAFT_0190923 Peptide, DDBDRAFT_0304991 Peptide, DDB_0190923 Peptide, DDB_0304991 Peptide, 4930584B20Rik Peptide, A930035J23Rik Peptide, AI047573 Peptide, AL024412 Peptide, AU014659 Peptide, Amp2 Peptide, Mnpep Peptide, p67 Peptide, p67eIF2 Peptide, MAP2 Peptide, MNPEP Peptide, wu:fb98h06 Peptide, zgc:66250 Peptide, methionyl aminopeptidase 2 L homeolog Peptide, methionyl aminopeptidase 2 Peptide, methionine aminopeptidase 2 Peptide, methionine aminopeptidase Peptide, methionyl aminopeptidase 2 S homeolog Peptide, methionyl aminopeptidase 2b Peptide, metap2.L Peptide, METAP2 Peptide, metap2 Peptide, LOC551771 Peptide, CAALFM_C604080WA Peptide, Metap2 Peptide, metap2.S Peptide, metap2b Peptide
    背景
    METAP2 is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site.This gene is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: MAP2, MNPEP, p67, p67eIF2

    Protein Interaction Partner: E2F4,CDC42,EIF2AK2,EIF2S3,MAPK1,MAPK3,RAC1,S100A4,EIF2AK2

    Protein Size: 478
    分子量
    53 kDa
    基因ID
    10988
    NCBI登录号
    NM_006838, NP_006829
    UniProt
    P50579
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