IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3) Peptide
IKZF3
适用: 人
宿主: 合成
BP, WB, IHC
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- 抗原 See all IKZF3 products
- IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-IKZF3 antibody (Catalog #: ARP39004_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))
- 别名
- AIO Peptide, AIOLOS Peptide, ZNFN1A3 Peptide, aio Peptide, aiolos Peptide, znfn1a3 Peptide, IKZF3 Peptide, 5830411O07Rik Peptide, Aiolos Peptide, Zfpn1a3 Peptide, Znfn1a3 Peptide, IKAROS family zinc finger 3 Peptide, IKAROS family zinc finger 3 L homeolog Peptide, IKZF3 Peptide, ikzf3.L Peptide, Ikzf3 Peptide
- 背景
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IKZF3 is a member of the Ikaros family of zinc-finger proteins. It is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers.This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoetic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.
Alias Symbols: AIO, AIOLOS, ZNFN1A3
Protein Interaction Partner: BCL2L1,CHD3,HRAS,IKZF1,IKZF3,IKZF4,IKZF5,RBBP8,UBE2I,BCL2L1,CHD4,HDAC2,HDAC4,HDAC5,HDAC7,HRAS,IKZF2,IKZF4,IKZF5,SIN3A,SIN3B,UBE2I
Protein Size: 453 - 分子量
- 52 kDa
- 基因ID
- 22806
- NCBI登录号
- NM_183228, NP_899051
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