A synthetic peptide for use as a blocking control in assays to test for specificity of IKZF3 antibody, Alternative Names: IKZF3 control peptide, IKZF3 antibody Blocking Peptide, Anti-IKZF3 Blocking Peptide, IKAROS family zinc finger 3, Aiolos Blocking Peptide, AIOLOS Blocking Peptide, ZNFN1A3 Blocking Peptide, IKZF3, IKZF-3, IKZF 3, IKZF-3 Blocking Peptide, IKZF 3 Blocking Peptide
IKZF3 is a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoetic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.