Isoleucyl-tRNA Synthetase (IARS) (Middle Region) Peptide
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Quick Overview for Isoleucyl-tRNA Synthetase (IARS) (Middle Region) Peptide (ABIN978371)
抗原
宿主
资源
应用范围
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蛋白结构域
- Middle Region
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序列
- YEAAKVFGLR SRKLKLFLNE TQTQEITEDI PVKTLNMKTV YVSVLPTTAD
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产品特性
- This is a synthetic peptide designed for use in combination with anti-IARS Antibody(ARP54954_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- IARS (Isoleucyl-tRNA Synthetase (IARS))
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背景
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Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Two alternatively spliced variants have been isolated that represent alternate 5' UTRs.
Alias Symbols: FLJ20736, IARS1, ILRS, PRO0785, IRS, ILERS
Protein Interaction Partner: AR,EPRS,GARS,AIMP2,AKTIP,BCAR3,EPRS,GARS,GSTK1,MAGED1,MCC,SGK1,SNCA,TRAF6,TSC22D1,USP19,VHL
Protein Size: 1262 -
分子量
- 144 kDa
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基因ID
- 3376
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NCBI登录号
- NM_013417, NP_038203
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UniProt
- P41252
抗原
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