Isoleucyl-tRNA Synthetase (IARS) Peptide
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北京 101111
Quick Overview for Isoleucyl-tRNA Synthetase (IARS) Peptide (ABIN936037)
抗原
宿主
资源
应用范围
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蛋白类型
- Synthetic
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序列
- YEAAKVFGLR SRKLKLFLNE TQTQEITEDI PVKTLNMKTV YVSVLPTTAD
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of IARS antibody,
Alternative Names: IARS control peptide, IARS antibody Blocking Peptide, Anti-IARS Blocking Peptide, Isoleucyl-tRNA Synthetase Blocking Peptide, FLJ20736 Blocking Peptide, IARS1 Blocking Peptide, ILRS Blocking Peptide, PRO0785 Blocking Peptide -
纯化方法
- Affinity chromatography using phosphopeptide and cross-adsorbed with the corresponding non-phosphopeptide.
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- IARS (Isoleucyl-tRNA Synthetase (IARS))
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背景
- Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Two alternatively spliced variants have been isolated that represent alternate 5' UTRs.
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分子量
- 144 kDa
抗原
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