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Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU) (C-Term) Peptide

HNRNPU 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN978094
发货至: 中国
  • 抗原 See all HNRNPU products
    HNRNPU (Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU))
    蛋白结构域
    C-Term
    宿主
    资源
    • 3
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    EITYVELQKE EAQKLLEQYK EESKKALPPE KKQNTGSKKS NKNKSGKNQF
    产品特性
    This is a synthetic peptide designed for use in combination with anti-HNRNPU Antibody(ARP40518_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    HNRNPU (Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU))
    背景
    HNRNPU belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. HNRNPU contains a RNA binding domain and scaffold-associated region (SAR)-specific bipartite DNA-binding domain. This protein is also thought to be involved in the packaging of hnRNA into large ribonucleoprotein complexes. During apoptosis, this protein is cleaved in a caspase-dependent way. But this cleavage does not affect the function of the encoded protein in RNA metabolism.

    Alias Symbols: HNRPU, SAF-A, U21.1, hnRNP U

    Protein Interaction Partner: ACTB,CR2,ACTB,BTRC,CASP3,CD5,CR2,ELL,EP300,GRIN1,GRIN2D,GTF2H1,NDN,NDRG1,NR3C1,POU3F4,PRMT1,PTPN11,SMN2,SREK1,STAU1,SYK,YAP1,ZNF689,CDK7,CDK9,EP300,GPN1,GTF2F1,HNRNPH1,MAX,MYC,NDN,NR3C1,POLR2A,POLR2J,POU3F4,PRMT1,RUVBL2,SFN

    Protein Size: 825
    分子量
    90 kDa
    基因ID
    3192
    NCBI登录号
    NM_031844, NP_114032
    UniProt
    Q00839
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