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High Mobility Group AT-Hook 1 (HMGA1) (N-Term) Peptide

HMGA1 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN978048
发货至: 中国
  • 抗原 See all HMGA1 products
    HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))
    蛋白结构域
    N-Term
    宿主
    资源
    • 7
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    MSESSSKSSQ PLASKQEKDG TEKRGRGRPR KQPPKEPSEV PTPKRPRGRP
    产品特性
    This is a synthetic peptide designed for use in combination with anti-HMGA1 Antibody(ARP38111_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))
    别名
    HMG-R Peptide, HMGA1A Peptide, HMGIY Peptide, Hmgi Peptide, Hmgiy Peptide, hmga1 Peptide, hmgiy Peptide, wu:fb12b06 Peptide, wu:fb18f11 Peptide, wu:fc19f01 Peptide, wu:fi38b05 Peptide, zgc:85677 Peptide, AL023995 Peptide, Hmga1a Peptide, Hmga1b Peptide, Hmgy Peptide, HMG-I(Y) Peptide, HMG-Y Peptide, HMGA1 Peptide, zgc:153948 Peptide, high mobility group AT-hook 1 Peptide, high mobility group protein HMG-I/HMG-Y Peptide, high mobility group AT-hook 1a Peptide, high mobility group AT-hook 1b Peptide, HMGA1 Peptide, Hmga1 Peptide, TSC_c24220 Peptide, hmga1a Peptide, LOC705105 Peptide, hmga1b Peptide
    背景
    This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene.

    Alias Symbols: HMG-R, HMGA1A, HMGIY, MGC12816, MGC4242, MGC4854

    Protein Interaction Partner: ATF2,CDK1,CEBPB,CREBBP,CSNK2A1,CSNK2A2,ELF1,EWSR1,HIPK2,IRF1,JUN,NFYA,POU3F1,PPARG,PRMT6,RARG,RNF4,RXRA,SP1,SRF,SUFU,ATF2,BANF1,CEBPB,CHD1,ELF1,EWSR1,INSR,IRF1,JUN,NFYA,NPM1,PARP1,POU3F1,PPARG,PRMT6,SP1

    Protein Size: 96
    分子量
    11 kDa
    基因ID
    3159
    NCBI登录号
    NM_002131, NP_002122
    UniProt
    Q5T6U8
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