High Mobility Group AT-Hook 1 (HMGA1) (N-Term) Peptide
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Quick Overview for High Mobility Group AT-Hook 1 (HMGA1) (N-Term) Peptide (ABIN8102504)
抗原
宿主
资源
应用范围
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蛋白结构域
- N-Term
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原理
- HMGA1 Peptide - N-terminal region
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序列
- MSESSSKSSQ PLASKQEKDG TEKRGRGRPR KQPPKEPSEV PTPKRPRGRP
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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This is a synthetic peptide designed for use in combination with anti-HMGA1 Antibody(ARP38111_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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缓冲液
- Lyophilized powder
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))
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背景
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Background Information: This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene.
Alternative Symbols: HMG-R, HMGA1A, HMGIY, MGC12816, MGC4242, MGC4854
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分子量
- 11kDa
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基因ID
- 3159
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NCBI登录号
- NP_002122
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UniProt
- Q5T6U8
抗原
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