Glutamate Receptor, Metabotropic 7 (GRM7) (C-Term) Peptide
GRM7
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN977702
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Quick Overview for Glutamate Receptor, Metabotropic 7 (GRM7) (C-Term) Peptide (ABIN977702)
抗原
GRM7
(Glutamate Receptor, Metabotropic 7 (GRM7))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- C-Term
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序列
- HPELNVQKRK RSFKAVVTAA TMSSRLSHKP SDRPNGEAKT ELCENVDPNS
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产品特性
- This is a synthetic peptide designed for use in combination with anti-GRM7 Antibody(ARP59604_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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Glutamate Receptor, Metabotropic 7 (GRM7) peptide
GRM7 适用: 人, 小鼠, 大鼠 宿主: 合成 BP, Imm
Glutamate Receptor, Metabotropic 7 (GRM7) peptideGRM7 宿主: 合成 BP, WB, IHC
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))
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背景
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L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: FLJ40498, GLUR7, GPRC1G, MGLU7, MGLUR7
Protein Interaction Partner: GRIP1,PICK1,SDCBP,CALM1,CALM3,CALM3,FLNA,GNAQ,GRIPAP1,PICK1,TUBA1A,TUBA1B,TUBA3C,TUBA4A,TUBA8,GNAQ,PICK1,PRKCA
Protein Size: 915 -
分子量
- 99 kDa
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基因ID
- 2917
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NCBI登录号
- NM_000844, NP_000835
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UniProt
- Q14831
抗原
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