Glutamate Receptor, Metabotropic 7 (GRM7) Peptide
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北京 101111
Quick Overview for Glutamate Receptor, Metabotropic 7 (GRM7) Peptide (ABIN939194)
抗原
宿主
资源
应用范围
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蛋白类型
- Synthetic
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序列
- HPELNVQKRK RSFKAVVTAA TMSSRLSHKP SDRPNGEAKT ELCENVDPNS
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of GRM7 antibody,
Alternative Names: GRM7 control peptide, GRM7 antibody Blocking Peptide, Anti-GRM7 Blocking Peptide, glutamate receptor, metabotropic 7 Blocking Peptide, FLJ40498 Blocking Peptide, GLUR7 Blocking Peptide, GPRC1G Blocking Peptide, MGLU7 Blocking Peptide, MGLUR7 Blocking Peptide, GRM7, GRM-7, GRM 7, GRM-7 Blocking Peptide, GRM 7 Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))
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背景
- L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene.
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分子量
- 99 kDa
抗原
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