This is a synthetic peptide designed for use in combination with anti-E2F1 antibody (Catalog #: AVARP04006_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
浓度
1 mg/mL
缓冲液
Final peptide concentration is 1 mg/mL in PBS.
注意事项
Avoid repeated freeze-thaw cycles.
储存条件
-20 °C
储存方法
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
抗原
E2F1
(E2F Transcription Factor 1 (E2F1))
背景
The protein encoded by E2F1 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis.
Alias Symbols: RBP3, E2F-1, RBAP1, RBBP3
Protein Interaction Partner: E2F2,E2F4,RBL2,BARD1,BIRC5,BRCA1,CBX5,CCDC76,CCNA1,CCNA2,CDC25A,CDC6,CDK1,CDKN2A,CEBPD,CEBPE,CHEK1,CSDA,E2F1,EAPP,FHL2,GAB2,GAS2L1,HIST1H2AG,HIST1H2BJ,HIST2H4A,JMY,MAD2L1,MAD2L1,MDM4,MFAP1,MLH1,MSH2,MSH2,MT1G,MYBL2,MYC,NCOA3,PPP1R13B,PPP1R13B,PRR11,RAD51,RAD54L,RB1,RB1,RB1,RB1,RB1,RB1,RBL1,RBL2,RECQL,TFDP1,TP53BP2,TP53BP2,TP53INP1,TTK,TYMS,UXT,ARID3A,ATM,ATR,BRCA1,BRD2,CCNA1,CCNA2,CDK1,CDK3,CDK7,CDKN2A,CEBPE,CHEK2,CREBBP,CTDP1,CUL1,DDB2,E2F6,GTF2H1,KAT5,MDM4,MNAT1,NCOA3,NCOA6,NDN,NFKB1,NPDC1,PARP1,PHB,PURA,RB1,SERTAD2,SKP2,SP1,SP2,SP3,SP4,TFDP1,TFDP2,TOPBP1,TP53,TP53BP1,TRRAP,ARID3A,BRD2,CCNA1,CCNA2,CDK2,CDK7,CDT1,CREBBP,CUL1,DNMT1,FHL2,GSK3B,GTF2H1,HDAC1,MDM4,MGA,MYBL2,NCOA6,NDN,NDNL2,NFKB1,NPDC1,Nfkb1,PHB,PKIB,PURA,RB1,RBBP4,RBL1,RING1,RNF144A,SKP2,SP1,SP2,SP3,SP4,SPIB,Sp1,TEAD3,TFDP1,TFDP2,TOPBP1,TP53BP1,TRRAP,UBC