Dickkopf 2 Homolog (DKK2) (Middle Region) Peptide
DKK2
适用: 小鼠
宿主: 合成
BP, WB
产品编号 ABIN975816
发货至:
中国
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Contact Info
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Quick Overview for Dickkopf 2 Homolog (DKK2) (Middle Region) Peptide (ABIN975816)
抗原
DKK2
(Dickkopf 2 Homolog (DKK2))
宿主
小鼠
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- NGICIPVTES ILTPHIPALD GTRHRDRNHG HYSNHDLGWQ NLGRPHSKMP
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产品特性
- This is a synthetic peptide designed for use in combination with anti-Dkk2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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Dickkopf 2 Homolog (DKK2) peptide
DKK2 适用: 人, 小鼠, Cow, 犬, 大鼠 宿主: 合成 BP, Imm
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DKK2 (Dickkopf 2 Homolog (DKK2))
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背景
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Dkk2 antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer's disease.
Alias Symbols: -
Protein Size: 259 -
分子量
- 28 kDa
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基因ID
- 56811
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NCBI登录号
- NM_020265, NP_064661
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UniProt
- Q9QYZ8
抗原
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