Dickkopf 2 Homolog (DKK2) (C-Term) Peptide
DKK2
适用: 人, 小鼠
宿主: 合成
BP, WB
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- 抗原 See all DKK2 products
- DKK2 (Dickkopf 2 Homolog (DKK2))
- 蛋白结构域
- C-Term
- 宿主
- 人, 小鼠
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- RTSDCGPGLC CARHFWTKIC KPVLREGQVC SRRGHKDTAQ APEIFQRCDC
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-Dkk4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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Dickkopf 2 Homolog (DKK2) peptide
DKK2 适用: 人, 小鼠, Cow, 犬, 大鼠 宿主: 合成 BP, Imm
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- DKK2 (Dickkopf 2 Homolog (DKK2))
- 别名
- DKK-2 Peptide, Dkk4 Peptide, zgc:171574 Peptide, dickkopf WNT signaling pathway inhibitor 2 Peptide, DKK2 Peptide, Dkk2 Peptide, dkk2 Peptide
- 背景
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Dkk4 antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
Alias Symbols: Dkk-4, MGC25705
Protein Size: 221 - 分子量
- 24 kDa
- 基因ID
- 234130
- NCBI登录号
- NM_145592, NP_663567
- UniProt
- Q8VEJ3
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