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CD8a Molecule (CD8A) (Middle Region) Peptide

CD8A 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN974701
发货至: 中国
  • 抗原 See all CD8 alpha (CD8A) products
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
    蛋白结构域
    Middle Region
    宿主
    资源
    • 4
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    GKRLGDTFVL TLSDFRRENE GYYFCSALSN SIMYFSHFVP VFLPAKPTTT
    产品特性
    This is a synthetic peptide designed for use in combination with anti-CD8A Antibody(ARP59114_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
    别名
    cd8 Peptide, LOC100136450 Peptide, BB154331 Peptide, Ly-2 Peptide, Ly-35 Peptide, Ly-B Peptide, Lyt-2 Peptide, zgc:136643 Peptide, CD8 Peptide, Leu2 Peptide, MAL Peptide, p32 Peptide, RHACD8-4 Peptide, CD8a molecule Peptide, uncharacterized LOC100125537 Peptide, CD8 alpha Peptide, CD8 antigen, alpha chain Peptide, T-cell surface glycoprotein CD8 alpha chain Peptide, Cd8a Peptide, LOC100125537 Peptide, LOC100136450 Peptide, CD8A Peptide, cd8a Peptide, LOC100126556 Peptide
    背景
    The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a corepressor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains, or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Multiple transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: CD8, Leu2, MAL, p32

    Protein Interaction Partner: B2M,CD3D,CD8A,CD8B,HLA-A,HLA-B,HLA-C,HLA-E,HLA-G,LAT,LCK,LGALS1,PTPRC,SREK1,SRSF1,CD3D,CD59,CD8A,CD8B,HLA-A,HLA-B,HLA-C,HLA-G,PTPRC

    Protein Size: 235
    分子量
    24 kDa
    基因ID
    925
    NCBI登录号
    NM_001145873, NP_001139345
    UniProt
    P01732
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