CD8a Molecule (CD8A) (Middle Region) Peptide
CD8A
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN974700
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
Quick Overview for CD8a Molecule (CD8A) (Middle Region) Peptide (ABIN974700)
抗原
CD8 alpha (CD8A)
(CD8a Molecule (CD8A))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- RGAAASPTFL LYLSQNKPKA AEGLDTQRFS GKRLGDTFVL TLSDFRRENE
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产品特性
- This is a synthetic peptide designed for use in combination with anti-CD8A Antibody(ARP59113_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
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背景
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The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a corepressor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains, or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CD8, Leu2, MAL, p32
Protein Interaction Partner: B2M,CD3D,CD8A,CD8B,HLA-A,HLA-B,HLA-C,HLA-E,HLA-G,LAT,LCK,LGALS1,PTPRC,SREK1,SRSF1,CD3D,CD59,CD8A,CD8B,HLA-A,HLA-B,HLA-C,HLA-G,PTPRC
Protein Size: 235 -
分子量
- 24 kDa
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基因ID
- 925
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NCBI登录号
- NM_001145873, NP_001139345
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UniProt
- P01732
抗原
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