Beta-secretase 1 (BACE1) (N-Term) Peptide
BACE1
适用: 人
宿主: 合成
BP, WB, IHC
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- 抗原 See all BACE1 products
- BACE1 (Beta-secretase 1 (BACE1))
- 蛋白结构域
- N-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-BACE1 antibody (Catalog #: ARP46851_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- BACE1 (Beta-secretase 1 (BACE1))
- 别名
- ASP2 Peptide, BACE Peptide, HSPC104 Peptide, C76936 Peptide, Bace Peptide, MGC145931 Peptide, BACE1 Peptide, zgc:77409 Peptide, beta-secretase 1 Peptide, beta-site APP cleaving enzyme 1 Peptide, beta-site APP-cleaving enzyme 1 Peptide, BACE1 Peptide, Bace1 Peptide, bace1 Peptide
- 背景
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Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein. BACE1, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Four transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: ASP2, BACE, FLJ90568, HSPC104, KIAA1149
Protein Interaction Partner: ATP1B1,CMPK1,ITM2C,KHSRP,NCSTN,PDIA3,PSAP,RANBP9,APP,ATP1B1,BRI3,CMPK1,CSNK1D,FURIN,GGA2,ITM2C,KHSRP,LRP1,MMP2,NCSTN,PDIA3,PLSCR1,PSAP,PSEN1,RANBP9,SELPLG,NCSTN
Protein Size: 501 - 分子量
- 51 kDa
- 基因ID
- 23621
- NCBI登录号
- NM_012104, NP_036236
- UniProt
- P56817
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