Beta-secretase 1 (BACE1) (Middle Region) Peptide
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Quick Overview for Beta-secretase 1 (BACE1) (Middle Region) Peptide (ABIN8095536)
抗原
宿主
资源
应用范围
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蛋白结构域
- Middle Region
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原理
- Bace1 Peptide - middle region
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序列
- YTPIRREWYY EVIIVRVEIN GQDLKMDCKE YNYDKSIVDS GTTNLRLPKK
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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This is a synthetic peptide designed for use in combination with anti-Bace1 Antibody,. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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缓冲液
- Lyophilized powder
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- BACE1 (Beta-secretase 1 (BACE1))
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背景
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Background Information: Bace1 is responsible for the proteolytic processing of the amyloid precursor protein (APP). Bace1 cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
Alternative Symbols: C76936
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分子量
- 56kDa
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基因ID
- 23821
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NCBI登录号
- NP_035922
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UniProt
- P56818
抗原
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