Actinin, alpha 4 (ACTN4) Peptide
ACTN4
适用: 人
宿主: 合成
BP, WB
-
- 抗原 See all alpha Actinin 4 (ACTN4) products
- alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
- 宿主
- 人
-
资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-ACTN4 antibody (Catalog #: ARP42203_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
-
-
- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- 抗原
- alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
- 别名
- fsgs Peptide, fsgs1 Peptide, C77391 Peptide, ACTININ-4 Peptide, FSGS Peptide, FSGS1 Peptide, wu:fb53f05 Peptide, zgc:63508 Peptide, actinin alpha 4 Peptide, actinin, alpha 4 Peptide, actinin alpha 4 S homeolog Peptide, actn4 Peptide, ACTN4 Peptide, Actn4 Peptide, actn4.S Peptide
- 背景
-
Alpha actinins belong to the spectrin superfamily which is a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. ACTN4 is a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in its gene have been associated with focal and segmental glomerulosclerosis.Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis.
Alias Symbols: DKFZp686K23158, FSGS, FSGS1, ACTININ-4
Protein Interaction Partner: CAMK2A,CAMK2B,LRRC7,PDLIM1,ACTC1,ACTN3,ADORA2A,ATP6V1B1,CAMK2A,CAMK2B,CAMK2G,COIL,COL17A1,GSN,ITGB1,LRRC7,MAGI1,MYOZ1,MYOZ2,NEB,NOS2,PDLIM1,PTPN11,PTPN6,SACS,SERPINE1,SLC2A4,SLC9A3R2,TJP1,TRIM3,USP6NL,CAMK2A,CAMK2B,COL17A1,GSN,INO80,Lrrc7,MAGI1,MYOZ1,MYOZ2,P2rx7,PDLIM1,SLC9A3R2,TRIM3,UBTF,USP6NL
Protein Size: 911 - 分子量
- 105 kDa
- 基因ID
- 81
- NCBI登录号
- NM_004924, NP_004915
- UniProt
- O43707
-
You are here:
