Actinin, alpha 4 (ACTN4) Peptide
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北京 101111
Quick Overview for Actinin, alpha 4 (ACTN4) Peptide (ABIN940431)
抗原
宿主
资源
应用范围
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蛋白类型
- Synthetic
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序列
- LIHRHRPELI EYDKLRKDDP VTNLNNAFEV AEKYLDIPKM LDAEDIVNTA
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of ACTN4 antibody,
Alternative Names: alpha Actinin 4 control peptide, alpha Actinin 4 antibody Blocking Peptide, Anti-alpha Actinin 4 Blocking Peptide, ACTN4 Blocking Peptide, DKFZp686K23158 Blocking Peptide, FSGS Blocking Peptide, FSGS1 Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
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背景
- Alpha actinins belong to the spectrin superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. ACTN4 is a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Alpha actinin is an actin-binding protein with multiple roles in different cell types.
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分子量
- 100 kDa
抗原
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