Toll-Like Receptor 4 (TLR4) Peptide
TLR4
适用: 哺乳动物
宿主: 合成
BP, WB, IHC
Quick Overview for Toll-Like Receptor 4 (TLR4) Peptide (ABIN940355)
抗原
TLR4
(Toll-Like Receptor 4 (TLR4))
宿主
哺乳动物
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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蛋白类型
- Synthetic
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序列
- LGEFRNEGNL EKFDKSALEG LCNLTIEEFR LAYLDYYLDD IIDLFNCLTN
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of TLR4 antibody,
Alternative Names: TLR4 control peptide, TLR4 antibody Blocking Peptide, Anti-TLR4 Blocking Peptide, toll-like receptor 4 Blocking Peptide, ARMD10 Blocking Peptide, CD284 Blocking Peptide, TOLL Blocking Peptide, hToll Blocking Peptide, TLR4, TLR-4, TLR 4, TLR-4 Blocking Peptide, TLR 4 Blocking Peptide
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Toll-Like Receptor 4 (TLR4) (AA 420-435) peptide (Ovalbumin)
TLR4 适用: 人 宿主: 合成 WB, Imm, SDS
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- TLR4 (Toll-Like Receptor 4 (TLR4))
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背景
- The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes. It has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Also, several transcript variants of this gene have been found, but the protein coding potential of most of them is uncertain.
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分子量
- 93 kDa
抗原
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