Toll-Like Receptor 4 (TLR4) (Middle Region) Peptide
TLR4
适用: 人
宿主: 合成
BP, WB, IHC
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- 抗原 See all TLR4 products
- TLR4 (Toll-Like Receptor 4 (TLR4))
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- LGEFRNEGNL EKFDKSALEG LCNLTIEEFR LAYLDYYLDD IIDLFNCLTN
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-TLR4 Antibody(ARP59041_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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Toll-Like Receptor 4 (TLR4) (AA 420-435) peptide (Ovalbumin)
TLR4 适用: 人 宿主: 合成 WB, Imm, SDS
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- TLR4 (Toll-Like Receptor 4 (TLR4))
- 别名
- ARMD10 Peptide, CD284 Peptide, TLR-4 Peptide, TOLL Peptide, Lps Peptide, Ly87 Peptide, Ran/M1 Peptide, Rasl2-8 Peptide, toll like receptor 4 Peptide, toll-like receptor 4 Peptide, TLR4 Peptide, Tlr4 Peptide
- 背景
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The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes. It has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Also, several transcript variants of this gene have been found, but the protein coding potential of most of them is uncertain.
Alias Symbols: ARMD10, CD284, TOLL, hToll
Protein Interaction Partner: BCL10,BTK,CD14,CNPY4,DEFB4A,HMGB1,HSP90B1,IRAK1,IRAK2,LY96,MAPK8IP3,MYD88,NOX4,RIPK2,RNF216,SIGIRR,SYK,TICAM2,TIRAP,TLR1,TLR5,TOLLIP,ECSIT,LY96,LY96,MYD88,PPP4C,RNF216,SIGIRR,TIRAP,TLR1,TOLLIP
Protein Size: 839 - 分子量
- 93 kDa
- 基因ID
- 7099
- NCBI登录号
- NM_138554, NP_612564
- UniProt
- O00206
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