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Crystallin, alpha B (CRYAB) Peptide

CRYAB 适用: 哺乳动物 宿主: 合成 BP, WB, IHC
产品编号 ABIN940136
发货至: 中国

Quick Overview for Crystallin, alpha B (CRYAB) Peptide (ABIN940136)

抗原

CRYAB (Crystallin, alpha B (CRYAB))

宿主

哺乳动物

资源

  • 6
合成

应用范围

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • 蛋白类型

    Synthetic

    序列

    KYRIPADVDP LTITSSLSSD GVLTVNGPRK QVSGPERTIP ITREEKPAVT

    产品特性

    A synthetic peptide for use as a blocking control in assays to test for specificity of CRYAB antibody,
    Alternative Names: Crystallin Alpha B control peptide, Crystallin Alpha B antibody Blocking Peptide, Anti-Crystallin Alpha B Blocking Peptide, CRYAB Blocking Peptide, CRYA2 Blocking Peptide, CTPP2 Blocking Peptide, HSPB5 Blocking Peptide
  • 应用备注

    Optimal conditions should be determined by the investigator

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C long term.
  • 抗原

    CRYAB (Crystallin, alpha B (CRYAB))

    背景

    Alpha crystallins are composed of: alpha-A and alpha-B, for acidic and basic, respectively. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone, instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-A and alpha-B are differentially expressed, alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases, a missense mutation cosegregated in a family with a desmin-related myopathy.

    分子量

    12 kDa
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