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Crystallin, alpha B (CRYAB) Peptide

CRYAB 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN975336
发货至: 中国
  • 抗原 See all CRYAB products
    CRYAB (Crystallin, alpha B (CRYAB))
    宿主
    资源
    • 6
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-CRYAB antibody (Catalog #: ARP48196_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    CRYAB (Crystallin, alpha B (CRYAB))
    别名
    CMD1II Peptide, CRYA2 Peptide, CTPP2 Peptide, CTRCT16 Peptide, HSPB5 Peptide, MFM2 Peptide, Crya-2 Peptide, Crya2 Peptide, HspB5 Peptide, AACRYA Peptide, CRYAB Peptide, cryab Peptide, cryab2 Peptide, wu:fe37f08 Peptide, zgc:91937 Peptide, crystallin alpha B Peptide, crystallin, alpha B Peptide, hypothetical protein Peptide, crystallin, alpha B, a Peptide, crystallin, alpha B, b Peptide, CRYAB Peptide, Cryab Peptide, ZK1128.7 Peptide, cryaba Peptide, cryabb Peptide
    背景
    Alpha crystallins are composed of: alpha-A and alpha-B, for acidic and basic, respectively. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone, instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-A and alpha-B are differentially expressed, alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases, a missense mutation cosegregated in a family with a desmin-related myopathy.

    Alias Symbols: CRYA2, CTPP2, HSPB5

    Protein Interaction Partner: BAX,BCL2L1,APP,BCL2L1,BMPR2,CRYAA,CRYAB,CRYBB2,CRYGC,CS,EPB41,HSPB1,PSMA3,TTN,BMPR2,CRYAA,CRYAB,CRYBB2,CRYGC,CS,HSPB1,HSPB2,PSMA3

    Protein Size: 108
    分子量
    12 kDa
    基因ID
    1410
    NCBI登录号
    NM_001885
    UniProt
    P02511
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