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O6-Methylguanine-DNA-Methyltransferase (MGMT) Peptide

MGMT 适用: 哺乳动物 宿主: 合成 BP, WB, IHC
产品编号 ABIN939556
发货至: 中国

Quick Overview for O6-Methylguanine-DNA-Methyltransferase (MGMT) Peptide (ABIN939556)

抗原

MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))

宿主

哺乳动物

资源

  • 2
合成

应用范围

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • 蛋白类型

    Synthetic

    序列

    ISYQQLAALA GNPKAARAVG GAMRGNPVPI LIPCHRVVCS SGAVGNYSGG

    产品特性

    A synthetic peptide for use as a blocking control in assays to test for specificity of MGMT antibody,
    Alternative Names: MGMT control peptide, MGMT antibody Blocking Peptide, Anti-MGMT Blocking Peptide, O-6-MethylRNA guanine-Dna Methyltransferase Blocking Peptide

    纯化方法

    The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
  • 应用备注

    Optimal conditions should be determined by the investigator

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    缓冲液

    PBS

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C long term.
  • 抗原

    MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))

    背景

    MGMT is involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA.MGMT repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

    分子量

    22 kDa
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