O6-Methylguanine-DNA-Methyltransferase (MGMT) Peptide
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北京 101111
Quick Overview for O6-Methylguanine-DNA-Methyltransferase (MGMT) Peptide (ABIN939556)
抗原
宿主
资源
应用范围
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蛋白类型
- Synthetic
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序列
- ISYQQLAALA GNPKAARAVG GAMRGNPVPI LIPCHRVVCS SGAVGNYSGG
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of MGMT antibody,
Alternative Names: MGMT control peptide, MGMT antibody Blocking Peptide, Anti-MGMT Blocking Peptide, O-6-MethylRNA guanine-Dna Methyltransferase Blocking Peptide -
纯化方法
- The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
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背景
- MGMT is involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA.MGMT repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
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分子量
- 22 kDa
抗原
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