A synthetic peptide for use as a blocking control in assays to test for specificity of PMS2 antibody, Alternative Names: PMS2 control peptide, PMS2 antibody Blocking Peptide, Anti-PMS2 Blocking Peptide, Pms2 Postmeiotic Segregation Increased 2 Blocking Peptide, HNPCC4 Blocking Peptide, PMS2CL Blocking Peptide, PMSL2 Blocking Peptide, PMS2, PMS-2, PMS 2, PMS-2 Blocking Peptide, PMS 2 Blocking Peptide
PMS2 is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors.