Interleukin 7 Receptor (IL7R) Peptide
IL7R
适用: 哺乳动物
宿主: 合成
BP, WB, IHC
产品编号 ABIN938111
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Quick Overview for Interleukin 7 Receptor (IL7R) Peptide (ABIN938111)
抗原
IL7R
(Interleukin 7 Receptor (IL7R))
宿主
哺乳动物
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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蛋白类型
- Synthetic
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序列
- ESFLDCQIHR VDDIQARDEV EGFLQDTFPQ QLEESEKQRL GGDVQSPNCP
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of IL7 R antibody,
Alternative Names: IL7R control peptide, IL7R antibody Blocking Peptide, Anti-IL7R Blocking Peptide, interleukin 7 receptor Blocking Peptide, CD127 Blocking Peptide, CDW127 Blocking Peptide, IL-7R-alpha Blocking Peptide, IL7RA Blocking Peptide, ILRA Blocking Peptide, IL7R, ILR-7, ILR 7, ILR-7 Blocking Peptide, ILR 7 Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- IL7R (Interleukin 7 Receptor (IL7R))
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背景
- The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID).
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分子量
- 49 kDa
抗原
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