Karyopherin (Importin) beta 1 (KPNB1) Peptide
KPNB1
适用: 哺乳动物
宿主: 合成
BP, WB, IHC
产品编号 ABIN937840
发货至:
中国
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Contact Info
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中国
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Quick Overview for Karyopherin (Importin) beta 1 (KPNB1) Peptide (ABIN937840)
抗原
KPNB1
(Karyopherin (Importin) beta 1 (KPNB1))
宿主
哺乳动物
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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蛋白类型
- Synthetic
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序列
- EHMKESTLEA IGYICQDIDP EQLQDKSNEI LTAIIQGMRK EEPSNNVKLA
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of KPNB1 antibody,
Alternative Names: KPNB1 control peptide, KPNB1 antibody Blocking Peptide, Anti-KPNB1 Blocking Peptide, karyopherin, importin beta 1 Blocking Peptide, IMB1 Blocking Peptide, IPO1 Blocking Peptide, IPOB Blocking Peptide, Impnb Blocking Peptide, MGC2155 Blocking Peptide, MGC2156 Blocking Peptide, MGC2157 Blocking Peptide, NTF97 Blocking Peptide, KPNB1, KPNB-1, KPNB 1, KPNB-1 Blocking Peptide, KPNB 1 Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))
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背景
- Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.
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分子量
- 96 kDa
抗原
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