A synthetic peptide for use as a blocking control in assays to test for specificity of NUP98 antibody, Alternative Names: NUP98 control peptide, NUP98 antibody Blocking Peptide, Anti-NUP98 Blocking Peptide, Nucleoporin 98Kda Blocking Peptide, ADIR2 Blocking Peptide, NUP196 Blocking Peptide, NUP98, NUP-98, NUP 98, NUP-98 Blocking Peptide, NUP 98 Blocking Peptide
The nuclear pore complex (NPC) is comprised of approximately 50 unique proteins collectively known as nucleoporins. The 98 kDa nucleoporin is localized to the nucleoplasmic side of the NPC. Rat studies show that the 98 kDa nucleoporin functions as one of several docking site nucleoporins of transport substrates. The human gene has been shown to fuse to several genes following chromsome translocatons in acute myelogenous leukemia (AML) and T-cell acute lymphocytic leukemia (T-ALL).