TNF Receptor-Associated Factor 6 (TRAF6) Peptide
TRAF6
适用: 哺乳动物
宿主: 合成
BP, WB, IHC
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- 抗原 See all TRAF6 products
- TRAF6 (TNF Receptor-Associated Factor 6 (TRAF6))
- 蛋白类型
- Synthetic
- 宿主
- 哺乳动物
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- YVTFMHLEAL RQRTFIKDDT LLVRCEVSTR FDMGSLRREG FQPRSTDAGV
- 产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of TRAF6 antibody,
Alternative Names: TRAF6 control peptide, TRAF6 antibody Blocking Peptide, Anti-TRAF6 Blocking Peptide, TNF receptor-associated factor 6 Blocking Peptide, MGC:3310 Blocking Peptide, RNF85 Blocking Peptide, TRAF6, TRAF-6, TRAF 6, TRAF-6 Blocking Peptide, TRAF 6 Blocking Peptide
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- 应用备注
- Optimal conditions should be determined by the investigator
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- 缓冲液
- PBS
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C long term.
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- 抗原
- TRAF6 (TNF Receptor-Associated Factor 6 (TRAF6))
- 背景
- TRAF6 is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein mediates the signaling not only from the members of the TNF receptor superfamily, but also from the members of the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein.
- 分子量
- 59 kDa
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