TNF Receptor-Associated Factor 6 (TRAF6) (Middle Region) Peptide
TRAF6
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all TRAF6 products
- TRAF6 (TNF Receptor-Associated Factor 6 (TRAF6))
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-TRAF6 antibody (Catalog #: ARP30226_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- TRAF6 (TNF Receptor-Associated Factor 6 (TRAF6))
- 别名
- MGC:3310 Peptide, RNF85 Peptide, 2310003F17Rik Peptide, AI851288 Peptide, C630032O20Rik Peptide, rnf85 Peptide, traf6 Peptide, xtraf6 Peptide, CG10961 Peptide, DTRAF2 Peptide, Dmel\\CG10961 Peptide, TRAF Peptide, TRAF2 Peptide, TRAF6 Peptide, Traf2 Peptide, dTRAF2 Peptide, dTRAF6 Peptide, dTraf2 Peptide, dtraf2 Peptide, GB10539 Peptide, fi15f02 Peptide, wu:fi15f02 Peptide, zgc:63704 Peptide, TNF receptor associated factor 6 Peptide, TNF receptor-associated factor 6 Peptide, TNF receptor associated factor 6 L homeolog Peptide, TNF-receptor-associated factor 6 Peptide, TNF receptor associated factor 6 S homeolog Peptide, TRAF6 Peptide, Traf6 Peptide, traf6.L Peptide, traf6 Peptide, LOC551819 Peptide, traf6.S Peptide
- 背景
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TRAF6 is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein mediates the signaling not only from the members of the TNF receptor superfamily, but also from the members of the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein.The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein mediates the signaling not only from the members of the TNF receptor superfamily, but also from the members of the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. Two alternatively spliced transcript variants encoding identical proteins have been reported.
Alias Symbols: MGC:3310, RNF85
Protein Interaction Partner: IRAK1,IRAK2,IRAK3,IRF7,MALT1,MAP3K14,TAB3,TICAM1,TICAM1,TICAM2,TRAF6,UBB,UBB,ZFAND5,ABL1,ATP6V1E1,CAV1,CBL,CD40,CYLD,ECSIT,EDA2R,FHL2,HSPA4,IL17RB,IRAK1,IRAK2,IRAK3,IRAK4,IRF5,IRF7,IRF8,KCNQ1,MALT1,MAP2K1,MAP2K6,MAP2K7,MAP3K14,MAP3K3,MAP3K5,MAP3K7,MAP3K8,MAPK14,MAPK8,MAST2,MAVS,MBP,NGFR,NGFRAP1,OTUD7B,PELI3,PRKCZ,PSMB5,PSMC1,PSMC2,PSMC3,PSMD1,PSMD12,PSMD13,PSMD6,PSMD7,PTPN6,RIPK2,SIGIRR,SPHK1,SQSTM1,SRC,STRADB,SYK,TAB1,TAB2,TAB3,TAX1BP1,TDP2,TICAM1,TICAM2,TIFA,TIRAP,TLR3,TMEM189-UBE2V1,TNFAIP3,TNFRSF11A,TNFRSF13B,TNFRSF19,TNFSF11,TRAF2,TRAF3IP2,TRAF4,TRAF6,TRAF7,TRAFD1,TRAM1,TRIM37,UBB,UBE2N,USP7,XIAP,ZFAND5,ZMYND11,ZNF675,ZRANB1,ASXL2,BMPR1B,CD40,CTPS,DDX3X,EDA2R,EIF4E2,EPPK1,Ecsit,FHL2,GANAB,HSPB2,IARS,IKBKG,IL17RA,IRAK1,IRAK2,IRAK3,IRAK4,KCNQ1,MAP3K14,MAP3K5,MAP3K7,MAST2,MCM7,MTHFD1,MYD88,Map3k7,NASP,NGFR,NTRK1,NTRK2,OTUD7B,PAICS,PELI3,PFAS,PPP4C,PRKCZ,PSEN1,PSMB5,PSMC1,PSMC2,PSMC3,PSMD1,PSMD12,PSMD13,PSMD3,PSMD7,RIPK2,RUNX1,SDCBP,SIGIRR,SPOP,SQSTM1,SRC,STRADB,SYK,TAB1,TAB2,TAB3,TARS,TAX1BP1,TDP2,TGFBR1,TIFA,TIRAP,TJP2,TNFAIP3,TNFRSF11A,TNFRSF13B,TRAF2,TRAF3IP1,TRAF6,TRIM37,UBC,UBE2N,UBE2V1,USP7,VARS,VCP,VDAC1,XIAP,ZFAND5,ZMYND11,ZNF675,ZRANB1
Protein Size: 522 - 分子量
- 59 kDa
- 基因ID
- 7189
- NCBI登录号
- NM_004620, NP_004611
- UniProt
- Q9Y4K3
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