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Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (Middle Region) Peptide

RRM2B 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN8110591
发货至: 中国
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Quick Overview for Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (Middle Region) Peptide (ABIN8110591)

抗原

RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))

宿主

人

资源

  • 4
合成

应用范围

Blocking Peptide (BP), Western Blotting (WB)
  • 蛋白结构域

    Middle Region

    原理

    RRM2B Peptide - middle region

    序列

    VHSEMYSLLI DTYIRDPKKR EFLFNAIETM PYVKKKADWA LRWIADRKST
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    This is a synthetic peptide designed for use in combination with anti-RRM2B Antibody (ARP46032_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    缓冲液

    Lyophilized powder

    储存条件

    -20 °C

    储存方法

    For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
  • 抗原

    RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))

    背景

    This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.

    分子量

    32kDa

    基因ID

    50484

    UniProt

    Q7LG56
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