Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (Middle Region) Peptide
RRM2B
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all RRM2B products
- RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- VHSEMYSLLI DTYIRDPKKR EFLFNAIETM PYVKKKADWA LRWIADRKST
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-RRM2B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
- 别名
- p53r2 Peptide, RRM2B Peptide, MTDPS8A Peptide, MTDPS8B Peptide, P53R2 Peptide, p53R2 Peptide, ribonucleotide reductase M2 B (TP53 inducible) S homeolog Peptide, ribonucleotide reductase regulatory TP53 inducible subunit M2B Peptide, ribonucleotide reductase M2 B (TP53 inducible) Peptide, rrm2b.S Peptide, RRM2B Peptide, rrm2b Peptide, Rrm2b Peptide
- 背景
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This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.
Protein Size: 299 - 基因ID
- 50484
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