Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2) (Middle Region) Peptide
PARK2
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all Parkin (PARK2) products
- Parkin (PARK2) (Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2))
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- SSSVLPGDSV GLAVILHTDS RKDSPPAGSP AGRSIYNSFY VYCKGPCQRV
- 产品特性
- This is a synthetic peptide designed for use in combination with anti- PARK2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- Parkin (PARK2) (Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2))
- 背景
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The precise function of this gene is unknown, however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support.
Alias Symbols: PDJ, AR-JP, LPRS2, PARK2
Protein Size: 437 - 基因ID
- 5071
- NCBI登录号
- NM_004562, NP_004553
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