Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (C-Term) Peptide
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Quick Overview for Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (C-Term) Peptide (ABIN5671856)
抗原
宿主
资源
应用范围
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蛋白结构域
- C-Term
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序列
- IEFVADRLLV ELGFSKVFQA ENPFDFMENI SLEGKTNFFE KRVSEYQRFA
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产品特性
- This is a synthetic peptide designed for use in combination with anti- RRM2B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
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背景
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This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.
Alias Symbols: P53R2, MTDPS8A, MTDPS8B
Protein Size: 299 -
基因ID
- 50484
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NCBI登录号
- NM_001172477, NP_001165948
抗原
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