Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2) (N-Term) Peptide
GAD2
适用: 人
宿主: 合成
WB
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- 抗原 See all GAD65 (GAD2) products
- GAD65 (GAD2) (Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))
- 蛋白结构域
- N-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Western Blotting (WB)
- 序列
- FWSFGSEDGS GDSENPGTAR AWCQVAQKFT GGIGNKLCAL LYGDAEKPAE
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- GAD65 (GAD2) (Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))
- 背景
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This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
Alias Symbols: GAD65,
Protein Size: 585 - 基因ID
- 2572
- NCBI登录号
- NM_000818, NP_000809
- UniProt
- Q05329
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