Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2) (N-Term) Peptide
GAD2
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all GAD65 (GAD2) products
- GAD65 (GAD2) (Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))
- 蛋白结构域
- N-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- FGSEDGSGDS ENPGTARAWC QVAQKFTGGI GNKLCALLYG DAEKPAESGG
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-DCE2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- GAD65 (GAD2) (Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))
- 别名
- GAD65 Peptide, gad65 Peptide, F12P19.12 Peptide, F12P19_12 Peptide, GLUTAMATE DECARBOXYLASE 2 Peptide, glutamate decarboxylase 2 Peptide, zgc:112198 Peptide, 6330404F12Rik Peptide, GAD(65) Peptide, Gad-2 Peptide, glutamate decarboxylase 2 Peptide, glutamate decarboxylase 1 Peptide, glutamic acid decarboxylase 2 Peptide, GAD2 Peptide, PTRG_06148 Peptide, LOC9324534 Peptide, Gad2 Peptide, GAD1 Peptide, gad2 Peptide
- 背景
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This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
Alias Symbols: GAD2,GAD65,
Protein Size: 585 - 基因ID
- 2572
- NCBI登录号
- NP_001127838
- UniProt
- Q05329
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