MHC Class I Polypeptide-Related Sequence A (MICA) (Middle Region) Peptide
MICA
适用: 人
宿主: 合成
BP, WB
-
- 抗原 See all MICA products
- MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
- 蛋白结构域
- Middle Region
- 宿主
- 人
-
资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- QKEGLHSLQE IRVCEIHEDN STRSSQHFYY DGELFLSQNL ETKEWTMPQS
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-MICA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- 抗原
- MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
- 别名
- MIC-A Peptide, PERB11.1 Peptide, MHC class I polypeptide-related sequence A Peptide, MICA Peptide
- 背景
-
This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants.
Alias Symbols: MIC-A, PERB11.1
Protein Size: 383 - 基因ID
- 100507436
- NCBI登录号
- NM_000247, NP_000238
- UniProt
- Q29983
-
You are here:
